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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NDC80
All Species:
26.06
Human Site:
T410
Identified Species:
44.1
UniProt:
O14777
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14777
NP_006092.1
642
73913
T410
R
G
K
E
A
I
E
T
Q
L
A
E
Y
H
K
Chimpanzee
Pan troglodytes
XP_512046
642
73980
T410
R
G
K
E
A
I
E
T
Q
L
A
E
Y
H
K
Rhesus Macaque
Macaca mulatta
XP_001086615
642
73921
T410
R
G
K
E
A
I
E
T
Q
L
A
E
Y
H
K
Dog
Lupus familis
XP_537313
642
73907
T410
R
G
K
E
A
I
E
T
Q
L
S
E
Y
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0F1
642
73943
A410
R
G
K
E
A
I
E
A
Q
L
A
E
Y
H
K
Rat
Rattus norvegicus
NP_001119742
329
38011
L111
K
L
A
R
K
L
K
L
I
P
K
G
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505423
649
75199
T412
R
S
K
E
G
I
E
T
Q
L
A
E
Y
H
K
Chicken
Gallus gallus
Q76I89
640
73723
T413
R
N
K
E
A
I
E
T
Q
L
A
E
Y
H
K
Frog
Xenopus laevis
Q8AWF5
638
74459
T408
K
M
K
E
S
V
E
T
Q
L
S
E
F
H
K
Zebra Danio
Brachydanio rerio
Q6DRJ7
632
73198
L406
K
T
K
E
K
A
E
L
K
V
A
E
Y
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17635
590
68894
D371
L
E
I
Q
S
E
L
D
R
L
S
K
E
T
W
Sea Urchin
Strong. purpuratus
XP_001197919
631
72734
R411
K
K
Q
E
E
L
E
R
K
V
N
A
Y
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40460
691
80469
D460
G
I
F
K
S
L
L
D
T
L
R
Q
Y
D
S
Red Bread Mold
Neurospora crassa
Q96U60
743
84837
R483
Q
R
L
D
E
L
E
R
L
V
E
K
Y
N
T
Conservation
Percent
Protein Identity:
100
99.6
99.2
92.5
N.A.
83.9
44.5
N.A.
75.5
71.3
56.8
44.2
N.A.
N.A.
N.A.
21.8
28
Protein Similarity:
100
99.6
99.5
97.1
N.A.
91.5
47.9
N.A.
87.9
84.7
77.4
63.8
N.A.
N.A.
N.A.
44.8
51.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
86.6
93.3
60
46.6
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
86.6
93.3
93.3
73.3
N.A.
N.A.
N.A.
40
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
22.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.1
44.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
43
8
0
8
0
0
50
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
15
0
0
0
0
0
8
0
% D
% Glu:
0
8
0
72
15
8
79
0
0
0
8
65
8
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
36
0
0
8
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% H
% Ile:
0
8
8
0
0
50
0
0
8
0
0
0
0
0
0
% I
% Lys:
29
8
65
8
15
0
8
0
15
0
8
15
0
0
65
% K
% Leu:
8
8
8
0
0
29
15
15
8
72
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
22
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
0
0
0
58
0
0
8
0
0
0
% Q
% Arg:
50
8
0
8
0
0
0
15
8
0
8
0
0
0
0
% R
% Ser:
0
8
0
0
22
0
0
0
0
0
22
0
0
0
15
% S
% Thr:
0
8
0
0
0
0
0
50
8
0
0
0
0
8
8
% T
% Val:
0
0
0
0
0
8
0
0
0
22
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
79
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _